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Psychopharmacological studies on Tragia involucrata root extract
A K Dhara1, S Pal, A K Nag Chaudhuri
1Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur University, Calcutta 700 032, India.
Phytotherapy Research : PTR
|July 12, 2002
Abstract:
The methanol fraction of the root extract of Tragia involucrata was investigated for psychopharmacological activity in rodents. It produced an alteration of behavioural pattern and a reduction in spontaneous motility. A significant potentiation of pentobarbitone-induced sleep, a decrease of body temperature, suppression of the aggressive behaviour pattern and of the conditioned avoidance response (CAR) were observed with the fraction. These suggest that the methanol fraction of the T. involucrata root extract possesses significant central nervous system depressant action.