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Convergent synthesis of an inner core GPI of sperm CD52
1Department of Chemistry, Case Western Reserve University, Cleveland OH 44106, USA.
Bioorganic & Medicinal Chemistry Letters
|July 13, 2002
Abstract:
An inner core of the GPI anchor of sperm CD52 antigens was synthesized by a highly convergent process using specially modified inositol, glucosamine and phospholipid as key building blocks. This paper also presents a new and efficient procedure to prepare 1,2,6-differentiated derivatives of inositol for GPI syntheses.