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Human In Vitro Suppression as Screening Tool for the Recognition of an Early State of Immune Imbalance
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Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells

Leonie S Taams1, Milica Vukmanovic-Stejic, Jay Smith

  • 1Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands. L.S.Taams@azu.nl

European Journal of Immunology
|July 13, 2002
PubMed
Summary

Human CD4+CD25+ T cells suppress immune responses to various antigens. These highly differentiated cells, generated in the periphery, play a key role in maintaining immune tolerance to diverse self, dietary, and foreign antigens.

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