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Updated: Aug 11, 2026

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
Published on: June 6, 2011
Hypertonic/hyperoncotic solution in hypovolemic patients: experience in the emergency room
Riad N Younes1, Dario Birolini
1Department of Surgery and LIM-62, Hospital das Clínicas, Faculty of Medicine, University of São Paulo.
Abstract:
Hypertonic solutions have been studied extensively in the treatment of hypovolemic shock, both in experimental and clinical models. Safety, efficacy, and long-term effects on animals and patients have been evaluated. The present article reviews indications, safety, mortality rates, and outcome in patients with hemorrhagic hypovolemic shock who were treated after admission with a hypertonic/hyperoncotic solution under strict observation in the emergency room.
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