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The design, synthesis and characterisation of channel-forming peptides
John M Sanderson1, Sarah Yazdani
1Department of Chemistry, University Science Laboratories, South Road, Durham, UK DH1 3LE. j.m.sanderson@durham.ac.uk
Abstract:
Synthetic peptides designed using criteria derived from statistical analyses of beta-barrel membrane proteins form channels in synthetic membranes at very low peptide:lipid ratios.