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Synthetic study on CP-263,114 (phomoidride B) by SET-mediated fragmentation
Takeshi Matsushita1, Hiroshi Ashida, Tetsutaro Kimachi
1Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.
Abstract:
Assembly of the highly functionalized carbocyclic core of CP-263,114 has been accomplished by using radical-mediated fragmentation with lithium naphthalenide as a key step.