Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dendritic cells.

Veronica Yao1, Cameron Platell, John C Hall

  • 1University Department of Surgery, Royal Perth Hospital, Perth, Western Australia, Australia.

ANZ Journal of Surgery
|July 19, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The promoting physical activity in regional and remote cancer survivors (PPARCS) trial: Physical activity maintenance.

Scandinavian journal of medicine & science in sports·2024
Same author

Acral Nodular Melanoma at a Site of Trauma.

Kansas journal of medicine·2023
Same author

Locally performed postoperative circulating tumour DNA testing performed during routine clinical care to predict recurrence of colorectal cancer.

ANZ journal of surgery·2023
Same author

Decreasing tobacco use promotes ulcer healing in a patient with Buerger's disease.

Clinical case reports·2023
Same author

A randomized controlled trial of Promoting Physical Activity in Regional and Remote Cancer Survivors (PPARCS).

Journal of sport and health science·2023
Same author

Syphilis presenting as exfoliative erythroderma.

International journal of dermatology·2022
Same journal

Clinical Outcomes of Non-Operative Versus Operative Treatment in Adhesive Small Bowel Obstruction: A Systematic Review and Meta-Analysis.

ANZ journal of surgery·2026
Same journal

How to Do It: Dual Irrigation-Drainage System for Drainage and Debridement of Pancreatic Necrosis Collections.

ANZ journal of surgery·2026
Same journal

Operating Theatre Waste Generation and Segregation in a Tertiary Hospital: A Prospective Waste Audit.

ANZ journal of surgery·2026
Same journal

Delayed Loop Ileostomy Reversal Increases the Risk of Colitis and Clostridium difficile Infection.

ANZ journal of surgery·2026
Same journal

Beyond the Ringing of the Bell in Pelvic Malignancy.

ANZ journal of surgery·2026
Same journal

Amputations in Sepsis Patients: A Population-Based Cohort Study of Rates and Risk Factors.

ANZ journal of surgery·2026
See all related articles

Dendritic cells (DCs) are key antigen-presenting cells (APCs) that initiate immune responses and prevent autoimmunity. Clinical studies show promise using DCs for cancer vaccination and treating various diseases.

Area of Science:

  • Immunology
  • Cell Biology
  • Clinical Research

Background:

  • Dendritic cells (DCs) are professional antigen-presenting cells (APCs) crucial for initiating immune responses.
  • DCs patrol tissues, capture antigens, and migrate to lymphoid organs to interact with lymphocytes.
  • They regulate both immune activation and self-tolerance, preventing autoimmune reactions.

Purpose of the Study:

  • To summarize the role of dendritic cells in initiating and regulating immune responses.
  • To highlight the therapeutic potential of dendritic cells in clinical applications.
  • To underscore the significance of DCs in both immunity and tolerance.

Main Methods:

  • Review of immunological functions of dendritic cells.
  • Analysis of clinical studies involving antigen-pulsed autologous DCs.

Related Experiment Videos

  • Examination of DC applications in transplantation, viral infections, and autoimmune diseases.

    • Main Results:

    • Dendritic cells effectively initiate T- and B-cell responses.
    • DCs play a critical role in tolerizing T cells to self-antigens, preventing autoimmunity.
    • Phase I and II studies demonstrate the promise of DC-based cancer vaccines.

    Conclusions:

    • Dendritic cells are vital for adaptive immunity and immune tolerance.
    • Antigen-pulsed autologous DCs show therapeutic promise in oncology.
    • DCs have broad applications in transplantation, infectious diseases, and autoimmune disorders.