Related Experiment Videos
Thinking beyond the tumor cell: Nf1 haploinsufficiency in the tumor environment
Margaret E McLaughlin1, Tyler Jacks
1Howard Hughes Medical Institute, Department of Biology and Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139, USA.
Cancer Cell
|July 19, 2002
Abstract:
Deletion of both copies of the Nf1 gene in Schwann cells combined with Nf1 heterozygosity in the tumor environment promotes neurofibroma formation in mice.