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Related Experiment Videos

Womens' preference in Down syndrome screening.

Irene M de Graaf1, Tjeerd Tijmstra, Otto P Bleker

  • 1Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands. I.M.degraaf@AMC.UvA.NL

Prenatal Diagnosis
|July 19, 2002
PubMed
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Pregnant women prefer first-trimester screening for Down syndrome using serum and ultrasound tests. Knowledge and acceptance of prenatal screening were lower in low-risk groups.

Area of Science:

  • Maternal-Fetal Medicine
  • Prenatal Diagnostics
  • Genetics

Background:

  • Understanding pregnant women's knowledge and preferences regarding prenatal tests is crucial for informed decision-making.
  • First-trimester screening offers earlier detection of fetal aneuploidies compared to second-trimester screening.

Purpose of the Study:

  • To assess pregnant women's knowledge of available prenatal tests for Down syndrome.
  • To determine pregnant women's preferences for first-trimester versus second-trimester screening.
  • To evaluate women's choices if offered specific prenatal diagnostic tests.

Main Methods:

  • A questionnaire was administered to pregnant women in a primary care setting (n=80) and at an academic medical center (n=195).
  • Participants were receiving antenatal care or had been offered prenatal diagnosis.

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  • Response rate exceeded 80%.

    • Main Results:

    • The majority of women preferred first-trimester screening for Down syndrome, specifically a combination of nuchal translucency measurement and serum screening.
    • Knowledge of Down syndrome screening options was lower among women in the low-risk group compared to the high-risk group.
    • Over 30% of low-risk women indicated they would decline a prenatal screening test offer.

    Conclusions:

    • Pregnant women favor first-trimester Down syndrome screening utilizing both ultrasound and serum markers.
    • Lower knowledge and acceptance rates of prenatal screening were observed in women at low risk for Down syndrome.
    • Targeted education may be necessary to improve understanding and uptake of prenatal screening in low-risk populations.