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Updated: Sep 30, 2026

Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
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Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular

W Taylor Kimberly1, Matthew J LaVoie, Beth L Ostaszewski

  • 1Program in Neuroscience, Harvard Medical School, Boston, Massachusetts 02115, USA.

The Journal of Biological Chemistry
|July 20, 2002
PubMed

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