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Related Experiment Videos

A quantitative analysis of sensory function in lumbar radiculopathy using current perception threshold testing.

Toshihiko Yamashita1, Kunihito Kanaya, Masatoshi Sekine

  • 1Department of Orthopaedic Surgery, Sapporo Medical University, Sapporo, Japan. tyamasit@sapmed.ac.jp

Spine
|July 20, 2002
PubMed
Summary

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Current perception threshold testing reveals sensory nerve dysfunction in lumbar radiculopathy patients. This quantitative method effectively measures A-beta, A-delta, and C fiber deterioration, aiding in diagnosis.

Area of Science:

  • Neurology
  • Neurosurgery
  • Orthopedics

Background:

  • Conventional methods for assessing sensory disturbance in spinal disorders are often subjective and difficult.
  • Quantitative sensory testing, such as current perception threshold (CPT) evaluation, offers a precise method for studying peripheral nerve dysfunction.
  • CPT analyzes the function of different nerve fiber types, including A-beta, A-delta, and C fibers.

Purpose of the Study:

  • To quantitatively evaluate the severity of sensory disturbance in patients diagnosed with lumbar radiculopathy.
  • To assess the utility of current perception threshold testing in identifying and quantifying sensory deficits.

Main Methods:

  • A study involving 48 patients with lumbar radiculopathy due to disc herniation and 11 healthy controls.

Related Experiment Videos

  • Peripheral sensory functions were assessed using current perception threshold testing at 2000, 250, and 5 Hz on the L5 and S1 dermatomes of both legs.
  • Pain intensity was measured using a visual analog scale.

    • Main Results:

    • Patients with lumbar radiculopathy exhibited significantly higher CPT values in affected legs compared to contralateral legs across all tested frequencies.
    • Affected legs in patients showed elevated CPT values at 2000 and 250 Hz compared to controls, indicating dysfunction in faster-conducting fibers.
    • Higher CPT values correlated with hypesthesia at 2000 and 250 Hz and with severe pain at 5 Hz.

    Conclusions:

    • Current perception threshold testing demonstrates significant deterioration of A-beta, A-delta, and C fiber functions in patients with lumbar radiculopathy.
    • This quantitative sensory testing technique is a valuable tool for objectively measuring and diagnosing sensory nerve dysfunction in radiculopathy.