Related Experiment Video
Updated: Aug 8, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
Buccodental pathology in patients with insulin-dependent diabetes mellitus: a clinical study
L Miralles-Jorda1, F J Silvestre-Donat, D M Grau Garcia-Moreno
1Master de Odontologia en Pacientes Especiales, Departamento de Estomatologia, Universidad de Valencia, Unidad de Estomatologia y Pacientes Especiales del Hospital Universitario Dr. Peset de Valencia, Spain.
Objective:
A study is made to determine whether patients with type 1 (insulin-dependent) diabetes mellitus (IDDM) suffer oral complications attributable to the disease, or whether some disorder of the oral cavity can be regarded as pathognomonic of diabetes.
Material And Methods:
Thirty juvenile diabetics and 30 healthy individuals were evaluated for dental caries and oral mucosal lesions, with the performance of basal and stimulated sialometry in all cases, to assess possible alterations in salivary flow. In addition, an study of periodontal variables was made such as the presence of bacterial plaque, gingival status and attachment losses.
Results And Conclusions:
The diabetics were found to have significantly greater periodontal attachment loss, even though oral hygiene was significantly better among these patients. There were no differences between the two groups in terms of the number of caries, the presence of mucosal lesions or salivary flow.
Related Concept Videos
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Diabetes: Symptoms, Diagnosis, and Complications
Type I Diabetes II: Pathophysiology
Type I Diabetes III: Clinical Manifestations
Type II Diabetes II: Pathophysiology
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis