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Synthesis and antimicrobial activity of new substituted anilinobenzimidazoles
Z M Nofal1, H H Fahmy, H S Mohamed
1Therapeutical Chemistry Dept, National Research Centre, Dokki, Cairo, Egypt.
Archives of Pharmacal Research
|July 24, 2002
Abstract:
A series of benzimidazole derivatives carrying different heterocycles such as 1,2,3-thiadiazole, 1,3,4-thiadiazole, thiazolidine, 2,3-dihydro-thiazole, 1,3,4-oxadiazole, semicarbazone and substituted thiosemi-carbazones were synthesized. Also a series of 1-methylbenzimidazole carrying hydroxy ethyl-amide, substituted sulfonyl hydrazide and benzoyl hydrazide from aminobenzoyl group at position 2 of 1-methylbenzimidazole were synthesized. The antimicrobial evaluation of some of the new compounds was carried out.