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Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
Evaluation of the analgesic activity of an ethanol extract of Miconia fallax
M L Andrade e Silva1, W R Cunha, C Pedro
1Núcleo de Pesquisa em Ciências Exatas e Tecnológicas da Universidade de Franca, SP, Brazil.
Bollettino Chimico Farmaceutico
|July 24, 2002
Abstract:
A significant analgesic effect was observed after oral administration of an ethanol extract of Miconia fallax to mice, evaluated using chemical (writhing test) and thermal (hot plate test) stimuli. The extract showed a significant effect compared to control in both algesimetric models, suggesting that it was efficient in increasing the pain threshold.
