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Feedback microwave thermotherapy versus TURP for clinical BPH--a randomized controlled multicenter study
Lennart Wagrell1, Sonny Schelin, Jorgen Nordling
1Department of Urology, Uppsala University Hospital, Uppsala, Sweden.
Urology
|July 26, 2002
Summary
Microwave thermotherapy (PLFT) showed comparable outcomes to TURP for benign prostatic hyperplasia (BPH) treatment. PLFT offers an advantage in simplicity and safety, making it an attractive alternative for BPH management.
Area of Science:
- Urology
- Minimally Invasive Therapies
- Medical Devices
Background:
- Benign prostatic hyperplasia (BPH) is a common condition in aging men.
- Transurethral resection of the prostate (TURP) is a standard surgical treatment for BPH.
- Alternative treatments with improved safety profiles are sought.
Purpose of the Study:
- To compare the efficacy and safety of ProstaLund Feedback Treatment (PLFT), a microwave thermotherapy, with TURP for BPH.
- To evaluate outcomes including symptom scores, urinary flow, and adverse events.
Main Methods:
- A randomized controlled multicenter study involving 154 patients with clinical BPH.
- Patients were randomized to PLFT or TURP (2:1 ratio).
- Outcomes assessed at 12 months included IPSS, Qmax, detrusor pressure, prostate volume, and adverse events.
Main Results:
- No significant differences in IPSS, Qmax, or detrusor pressure between PLFT and TURP at 12 months.
- Serious adverse events were significantly lower with PLFT (2%) compared to TURP (17%).
- Responder rates were high and comparable (82% for PLFT, 86% for TURP).
Conclusions:
- Microwave thermotherapy with intraprostatic temperature monitoring (PLFT) is comparable to TURP for BPH treatment outcomes.
- PLFT demonstrates advantages in simplicity and safety.
- PLFT presents an attractive alternative to TURP for BPH management within a one-year perspective.