Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Conjugated vaccines].

B Swennen1, J Sternon

  • 1Unité d'Epidémiologie pédiatrique et Vaccination, Ecole de Santé publique, U.L.B.

Revue Medicale De Bruxelles
|July 30, 2002
PubMed
Summary
This summary is machine-generated.

Conjugate vaccines enhance protection for young children against serious infections like Haemophilus influenzae type b, meningococcal C, and pneumococcal disease by converting T-independent antigens into T-dependent ones. This review examines their efficacy, focusing on antigen interference, immune response surrogates, herd immunity, and serotype replacement.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High number of hospitalisations and non-classical presentations: lessons learned from a measles outbreak in 2017, Belgium.

Epidemiology and infection·2020
Same author

Traitement Des Infections Bronchopulmonaires Aigues Par Le Laurylsulfate De Tetracycline Intra-Musculaire.

Acta clinica Belgica·2016
Same author

[Determinants of breastfeeding in the Brussels Region].

Revue medicale de Bruxelles·2015
Same author

Breastfeeding duration: a survival analysis-data from a regional immunization survey.

BioMed research international·2014
Same author

[Breastfeeding in the French-speaking community of Belgium (2009)].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2014
Same author

[Vaccination: cost-effectiveness ratio].

Revue medicale de Bruxelles·2009
Same journal

[Breast cancer screening : a tool for informed decision making].

Revue medicale de Bruxelles·2018
Same journal

[Breast cancer screening : present situation and prospects].

Revue medicale de Bruxelles·2018
Same journal

[Guidelines in medical imaging : objectives, limits and radiation protection].

Revue medicale de Bruxelles·2018
Same journal

[How to avoid overmedicalization of the elderly patient ?]

Revue medicale de Bruxelles·2018
Same journal

[Ethical, pedagogical, socio-political and anthropological implications of quaternary prevention].

Revue medicale de Bruxelles·2018
Same journal

[New strategies in specific care for benign prostatic hypertrophy in older men].

Revue medicale de Bruxelles·2018
See all related articles

Area of Science:

  • Immunology
  • Vaccinology
  • Pediatric Infectious Diseases

Context:

  • Conjugate vaccines are crucial for extending disease prevention in children under two years old.
  • They convert T-independent antigens into T-dependent ones, enabling robust immune responses.
  • This strategy protects against severe infections like Haemophilus influenzae type b, meningococcal C, and pneumococcal disease.

Purpose:

  • To review the efficacy and immunological responses of three key conjugate vaccines.
  • To address critical questions regarding antigen interference, serological correlates of protection, herd immunity, and serotype replacement.

Summary:

  • Conjugate vaccines link capsular polysaccharides to carrier proteins, enhancing immunogenicity in infants.
  • This review synthesizes data on Haemophilus influenzae type b, meningococcal C, and pneumococcal conjugate vaccines.

Related Experiment Videos

  • Key areas explored include immune interference, surrogate markers for protection, community-level effects (herd immunity), and shifts in circulating pathogen strains.

    • Impact:

    • Provides a comprehensive overview of conjugate vaccine performance and immunological considerations.
    • Informs public health strategies for childhood immunization programs.
    • Highlights areas for future research in vaccine development and implementation.