Related Experiment Video
Updated: Jul 30, 2026

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
Published on: October 2, 2012
[Regulation of 1-dehydrogenation and 20 beta-reduction of ketosteroids by microorganisms]
Abstract:
Regulation of two microbiological processes--1-dehydrogenation and 20 beta-reduction of ketosteroids--was studied using several exogeneous quinones which (a) stimulated 1-dehydrogenation and (b) inhibited the accompanying reaction, the reduction of 20-ketogroup of the steroid molecule. The least active compounds were benzoquinones. The best regulators are 1,4-naphthoquinone, 1,2-naphthoquinone, and 7-methoxy-1,2-naphthoquinone. Possible mechanism of the action of naphthoquinones on Mycobacterium globiforme is discussed.
Related Concept Videos
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Alcohols from Carbonyl Compounds: Reduction
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
Regulation of Metabolism
Drug Biotransformation: Overview
Phase I Reactions: Reductive Reactions
Lipid Catabolism

