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RNA interference: the new somatic cell genetics?
Patrick J Paddison1, Gregory J Hannon
1Cold Spring Harbor Laboratory, Watson School of Biological Sciences, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.
Cancer Cell
|August 2, 2002
Abstract:
RNAi is evolving into a powerful tool for manipulating gene expression in mammalian cells with potential utility for investigating gene function, for high-throughput, function-based genetic screens and potentially for development as a therapeutic tool.