Electrodiagnostic approach to the patient with suspected myopathy
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Updated: Sep 30, 2026

Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents
Published on: June 8, 2022
1Departments of Neurology and Pathology (Neuropathology), University of Pittsburgh, School of Medicine, 200 Lothrop Street, PUH F-878, Pittsburgh, PA 15213, USA. lacomis@np.awing.upmc.edu
Abstract:
Uncovering the cause of a suspected myopathy may be challenging. However, a careful approach starts with utilizing the wealth of available information regarding the clinical and laboratory features of myopathy. Electrodiagnostic testing is then obtained (in most cases). Recognition of the pattern of EMG findings in light of the clinical and laboratory features should narrow the differential diagnosis and dictate the next steps in the evaluation. Histopathologic or molecular studies, or both may follow. Ultimately, this approach usually allows the clinician to make the correct diagnosis.
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