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Updated: Mar 3, 2026

Tissue Triage and Freezing for Models of Skeletal Muscle Disease
Published on: July 15, 2014
What Is in the Myopathy Literature?
Michael Isfort1, David Lacomis2
1Department of Neurology, The Neuroscience Research Institute, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH; and.
Abstract:
This update begins with a discussion of treatable lipid storage myopathies associated with the use of sertraline and ranolazine. We then turn to monoclonal gammopathy-associated myopathies including a more recently identified disorder that is also treatment-responsive, monoclonal gammopathy-associated glycogen storage myopathy. Several reports on statins and muscle symptoms, toxic myopathy, and immune-mediated necrotizing myopathy follow. Other autoimmune myopathy topics are highlighted. Then, muscular dystrophies are covered with a focus on dystrophinopathies, limb-girdle muscular dystrophy, and facioscapulohumeral muscular dystrophy. Pompe disease follows with a focus on enzyme replacement therapy data. A short section on congenital myopathies precedes a review of reports on myotonic dystrophies and nondystrophic myotonias.
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