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Updated: Sep 30, 2026

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
Published on: June 9, 2018
[An anatomofunctional brain database]
Bénédicte Batrancourt1, Richard Levy, Stéphane Lehericy
1Inserm E 007, Centre de neuropsychologie, hôpital de la Salpêtrière, 47, bd de l'Hôpital, 75651 Paris, France. benedicte.batrancourt@psl.ap-hop-paris.fr
Abstract:
This study proposes a closer look at the neuropsychological method defined as the study of the neural bases of the behavioural and cognitive functions using an organisation-representation model for current data and knowledge of the brain, and the application of an anatomofunctional database. A Centre of Cognitive Anatomy (CAC) was set up for the collection and processing of neuronatomical, neuropsychological, and psycho-behavioural data for patients presenting sequels of focal brain damage. Such a system would allow concurrent treatment of anatomical and functional data. We would expect the results from such a model to produce stable 'anatomofunctional laws' that would be independent of all inter-individual variations in the functioning of the brain and could be checked against the entire database of information. A direct application would be the improvement of cognitive and/or behavioural rehabilitation of patients with brain damage.
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