Quantitative evaluation of carotid atherosclerotic plaques by magnetic resonance imaging

In order to study human atherosclerotic plaque burden and composition in vivo, an imaging technique is needed that can directly measure volume and characterize the cross-sectional morphologic components of the atherosclerotic arterial wall. High-resolution magnetic resonance imaging (MRI), which is noninvasive and nonirradiative, has been described as one promising modality to achieve these purposes. MRI allows direct visualization of the diseased vessel wall and is capable of characterizing the morphology of individual atherosclerotic carotid plaques.