[The origin of Barr-positive and Barr-negative dyshormonal tumors]

It has been found that females with dyshormonal tumors can be divided into two groups as to the incidence of sex chromatin in buccal mucosa. An existance of two groups differentiated by the sex chromatin incidence was also supported by the data obtained during examination of apparently healthy females of child-bearing age. The relationship has been established between the incidence of sex chromatin and certain features of the reproductive function. It may be assumed that the female population consists of two subgroups differentiated by a constitutional type of hormonal balance. Some evidences on population heterogeneity as concerns the factors determining the incidence of sex chromatin were obtained in studies of the latter conducted in males. We may suggest, therefore, the relationship between the two variants of dyshormonal tumors and two constitutional types of ageing.