Related Experiment Video
Updated: Jun 3, 2026

Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging
Published on: January 30, 2026
[Epigenetic epidemiology of age-related diseases]
Abstract:
Many studies have shown that our organism is mostly sensitive to different influences in pre- and postnatal periods of ontogenesis. During the critical periods of maturation, these influences induce changes in the organism that relate to ontogenetic plasticity and lead to permanent changes in structure and function of different organ systems of the organism. It is suggested that the main molecular mechanisms of so-called "ontogenetic programming" are based on changes that occur on the epigenetic level, including changes in the genetic expression not connected with modifications of DNA structure. The present review deals with experimental and epidemiologic evidences of the role of epigenetic processes in aging and determination of susceptibility to some age-related diseases, such as cancer, cardiovascular and neurodegenerative diseases, and insulin-independent diabetes.
Related Concept Videos
Epigenetic Regulation
X-chromosome...
Epigenetic Regulation
Epigenetic Regulation
Pharmacodynamics in Geriatric Patients: Effects of Age
The Effect of Aging on Tissues
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

