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Histologic features of surgically removed fallopian tubes.

Jennifer L Hunt1, Amy A A Lynn

  • 1Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 15213, USA. HUNTJL@msx.upmc.edu

Archives of Pathology & Laboratory Medicine
|August 13, 2002
PubMed
Summary

This study details common histologic changes in fallopian tubes, finding stromal alterations like fibrosis and edema, epithelial changes, and frequent inflammatory cells. These findings are valuable for surgical pathologists analyzing fallopian tube specimens.

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Area of Science:

  • Pathology
  • Histology
  • Gynecologic Pathology

Background:

  • Fallopian tube specimens are frequently encountered in pathology laboratories.
  • Common histologic findings require documentation and correlation with clinical history.

Purpose of the Study:

  • To document the frequency of histologic changes in fallopian tubes removed for various reasons.
  • To explore associations between histologic findings and clinical history.

Main Methods:

  • Review of 287 hematoxylin-eosin-stained fallopian tube specimens.
  • Identification and categorization of stromal, epithelial, and inflammatory changes.
  • Correlation of histologic findings with clinical history, surgery type, and patient age.

Main Results:

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  • Stromal and architectural alterations were most frequent, including plical fibrosis (35.5%) and intramuscular edema (12.5%).
  • Epithelial changes like atypia (7.3%) and vacuolization (6.6%) correlated with older age.
  • Inflammatory cells were common, with intramuscular mast cells in 69% and stromal plasma cells in 19.9%.

Conclusions:

  • Provides frequency data for common histologic changes in fallopian tubes.
  • Highlights associations between specific findings and clinical factors like age and postpartum status.
  • A valuable resource for surgical pathologists in characterizing fallopian tube histology.