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Ageing research in Greece.

E S Gonos1, D Agrafiotis, A S Dontas

  • 1Laboratory of Molecular and Cellular Ageing, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vas. Constantinou Avenue, 11635 Athens, Greece. sgonos@eie.gr

Experimental Gerontology
|August 15, 2002
PubMed
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Greek scientists are advancing ageing research through diverse studies on centenarians, cellular processes, and age-related diseases. Their work, recognized internationally, spans genetics, proteomics, and socio-cultural factors, aiming to deepen our understanding of the ageing process.

Area of Science:

  • Gerontology and Ageing Research
  • Molecular Biology
  • Biomedical Sciences

Background:

  • Greece has a well-established network of research groups dedicated to ageing.
  • These groups are situated in universities, research institutes, and public hospitals.
  • Their research covers a wide spectrum of ageing-related topics.

Purpose of the Study:

  • To summarize the diverse ageing research activities conducted in Greece.
  • To highlight the international recognition and funding of these research efforts.
  • To discuss future directions for advancing the field of ageing in Greece.

Main Methods:

  • Functional analysis of Clusterin/Apolipoprotein J.
  • Studies on protein degradation and the proteasome in senescence.

Related Experiment Videos

  • Nationwide studies on determinants and markers of successful ageing in centenarians.
  • Research on gene expression, acetylation, amyloid precursor protein, and Presenilin 1.
  • Investigation of oxidative stress-induced DNA damage and oncogenes in senescence.
  • Studies on connective tissue, proteomics, and model organisms (Caenorhabditis elegans).
  • Research on skin ageing due to ultraviolet radiation and socio-cultural aspects of ageing.
  • Main Results:

    • A comprehensive overview of ongoing ageing research in Greece is presented.
    • Research activities encompass molecular, cellular, and population-level studies.
    • Greek ageing research is internationally recognized, evidenced by publication records and funding.

    Conclusions:

    • Greece possesses a robust and multifaceted ageing research landscape.
    • Collaboration and continued investigation across various disciplines are crucial for future progress.
    • Further development of the ageing field in Greece is supported by international recognition and funding.