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Glycogen metabolism loss: a common marker of parasitic behaviour in bacteria?
Bernard Henrissat1, Emeline Deleury, Pedro M Coutinho
1Architecture et Fonction des Macromolécules Biologiques, UMR6098, CNRS, Universités de Marseille I and II, 31 Chemin Joseph Aiguier, 13402 Marseille cedex 20, France. bernie@afmb.cnrs-mrs.fr
Trends in Genetics : TIG
|August 15, 2002
Abstract:
We searched 55 completely sequenced bacterial genomes for glycogen synthesis and degradation enzymes. A significant proportion of these bacteria appears to lack glycogen metabolism capability. Interestingly, these bacteria are parasitic, symbiotic or fastidious (i.e. difficult to culture outside their normal environment). It is suggested that the lack of bacterial glycogen metabolism is a trait associated with parasitic behaviour in bacteria.