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Mitotic exit: the Cdc14 double cross
Marco Geymonat1, Sanne Jensen, Leland H Johnston
1Division of Yeast Genetics, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Current Biology : CB
|August 15, 2002
Abstract:
The release of Cdc14 from the nucleolus occurs in two waves in early and late anaphase, controlled by the FEAR and MEN pathways, respectively. Two new papers report the localisation at the spindle pole body of the Cdc14 released in early anaphase and, surprisingly, show that the two pulses of released Cdc14 have opposite effects on MEN activation.