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Chromatin: a connection between loops and barriers?
1Unit on Chromatin and Transcription, NICHD/NIH, Bldg. 18T, Rm. 106, 18 Library Drive, Bethesda, MD 20892, USA. Rohinton@helix.nih.gov
Current Biology : CB
|August 15, 2002
Abstract:
A genetic screen for proteins that can block the spread of silenced heterochromatin has identified components of the nuclear pores with potential barrier activity. These results suggest that formation of loops of chromatin anchored to the pore could be one mechanism of barrier function.