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Updated: Sep 30, 2026

A Standardized Murine Model with a Three-Person Workflow for Studying Acute Cellular and Antibody-Mediated Rejection in Xenotransplantation
Published on: March 20, 2026
["Take this heart away!": from fear of rejection to post-transplant delirium]
J M Triffaux1, J C Demoulin, R Limet
1Service de Psychiatrie et de Psychologie Médicale, CHU de Liège.
Abstract:
Orthotopic heart transplantation is a major surgical intervention inducing conscious and unconscious psychological distress. Though all reports indicated global improvement of quality of life from pre- to post-transplantation, most retrospective and longitudinal studies found a high prevalence of psychopathology before and after surgery. Post-operative acute psychotic disorders are uncommon but they severely hamper the medical progress and require an immediate psychiatric assistance. The case of Pascal, a young receiver who presented a brief persecution delusional disorder after the first transplantation, showed the dramatic character of such unexpected symptoms.
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