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Challenges in applying microarrays to environmental studies
Jizhong Zhou1, Dorothea K Thompson
1Environmental Sciences Division, Oak Ridge National Laboratory, PO Box 2008, Oak Ridge, TN 37831, USA. zhouj@ornl.gov
Current Opinion in Biotechnology
|August 16, 2002
Abstract:
Although DNA microarray technology has been used successfully to analyze global gene expression in pure cultures, it has not been rigorously tested and evaluated within the context of complex environmental samples. Adapting microarray hybridization for use in environmental studies faces several challenges associated with specificity, sensitivity and quantitation.