Skeletal muscle lymphoma

Lymphoma usually presents with painless lymphadenopathy. However, it can also present at an extranodal site. Presentation with skeletal muscle infiltration is relatively uncommon and can be confused with a wide variety of both inflammatory as well as neoplastic conditions. We report a patient who presented with progressive swelling of the lower extremity resembling inflammatory necrosis on computed tomography scan, but was later diagnosed as skeletal muscle lymphoma on biopsy.