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Total synthesis of proposed amphidinolide A via a highly selective ring-closing metathesis
Robert E Maleczka1, Lamont R Terrell, Feng Geng
1Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA. maleczka@cem.msu.edu
Organic Letters
|August 17, 2002
Abstract:
[structure: see text] A highly convergent synthesis of the proposed structure of amphidinolide A is reported. Instructive applications of several organometallic processes are illustrated, including a highly selective ring-closing metathesis reaction.