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Related Experiment Videos

Development of perfusion CT software for personal computers

Yoshito Tsushima1, Shintaro Funabasama, Shigeru Sanada

  • 1Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Hospital, Japan.

Academic Radiology
|August 21, 2002
PubMed
Summary

New software creates quantitative perfusion maps of upper abdominal organs using computed tomographic (CT) imaging. While arterial perfusion imaging shows good quality, portal perfusion CT images are often degraded by patient motion.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Computational Anatomy

Background:

  • Quantitative mapping of organ perfusion aids in diagnosing and managing upper abdominal diseases.
  • Computed tomographic (CT) imaging offers detailed anatomical visualization.

Purpose of the Study:

  • To develop and evaluate software for creating quantitative arterial and portal perfusion maps of upper abdominal organs using CT.
  • To assess the image quality of these perfusion CT images.

Main Methods:

  • Developed software for quantitative perfusion mapping on personal computers.
  • Acquired 91 dynamic CT studies from 58 patients with upper abdominal diseases.
  • Applied the maximum-slope method to generate perfusion maps and visually evaluated image quality.

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Main Results:

  • Arterial perfusion CT images were successfully created in 89% of examinations, with 81% rated as good or moderate quality.
  • Portal perfusion CT images were created in 68% of relevant examinations, but only 38% were rated as good or moderate quality.
  • Patient motion significantly degraded image quality in 7 arterial and 27 portal perfusion images.

Conclusions:

  • Perfusion CT enables the creation of quantitative perfusion maps with good anatomical detail.
  • Patient movement is a common limitation that frequently degrades the image quality of portal perfusion CT.