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Updated: Aug 3, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
[Carotid endarterectomy in chronic renal failure patients: report of two cases]
Katsumi Matsumoto1, Katsuhito Akagi, Makoto Abekura
1Department of Neurosurgery, Hanwa Memorial Hospital, 7-11-11, Karita, Sumiyoshi-ku, Osaka-city, Osaka 558-0011, Japan.
Insights
Carotid atherosclerosis is common in chronic renal failure patients. Carotid endarterectomy is a safe and effective treatment for severe carotid stenosis in these patients, despite potential risks.
Area of Science:
- Nephrology
- Vascular Surgery
- Neurology
Background:
- Chronic renal failure (CRF) is a significant risk factor for atherosclerosis, particularly affecting the carotid arteries.
- Carotid atherosclerosis can lead to serious neurological events like stroke and transient ischemic attacks.
Observation:
- Two cases of severe carotid bifurcation stenosis in patients undergoing long-term hemodialysis are presented.
- One patient experienced recurrent hemiparesis, while the other presented with vertigo.
Findings:
- Both patients underwent successful carotid endarterectomy (CEA) for bilateral or unilateral carotid stenosis.
- Postoperative recovery was uneventful, with no neurological deficits reported in either case.
- Despite reported higher complication rates in CRF patients, CEA proved safe and effective in these instances.
Implications:
- Carotid endarterectomy should be considered for patients with chronic renal failure and severe carotid stenosis.
- This intervention can mitigate the risk of stroke and improve neurological outcomes in this high-risk population.
- Further research into optimizing CEA in CRF patients is warranted to minimize potential complications.
Abstract:
Chronic renal failure is one of the risk factors for carotid atherosclerosis. We report two cases of stenosis of the carotid bifurcation treated by carotid endarterectomy. A 66-year-old man with a 17-year history of hemodialysis experienced repeated episodes of right hemiparesis. Cerebral angiography showed severe stenosis of the cervical carotid bifurcation bilaterally. Left and right carotid endarterectomy operations were performed one month apart. The postoperative course was uneventful, and the patient returned home without neurological symptoms. The second case was in a 49-year-old woman with a 15-year history of hemodialysis had vertigo of one month duration. Cerebral angiography revealed occlusion of the left subclavian artery, and the distal left axillary artery was filled by retrograde flow from the left vertebral artery. Stenosis of the right carotid bifurcation was also noted. Right carotid endarterectomy was performed without any complications. Although a high incidence of intraoperative complications and of recurrent stroke after carotid endarterectomy (CEA) has been reported in chronic renal failure patients, the poor prognosis of the natural history of severe carotid stenosis in chronic renal failure should be taken into consideration. The cases reported indicate that carotid endarterectomy is safe and justified for carotid stenosis in chronic renal failure patients.
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