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Changes of decartograms under gravitational acceleration and microgravity.
E V Blinova1, T A Sakhnova, E S Kozhemyakina
1Cardiology Research Complex, Ministry of Health of Russian Federation, University Bordeaux 2, University Paris 11.
Bratislavske Lekarske Listy
|August 23, 2002
Summary
The activation area (AA) of the heart
Area of Science:
- Cardiology
- Space Physiology
- Biomedical Engineering
Background:
- Orthogonal electrocardiograms (ECGs) provide insights into cardiac electrical activity.
- Parabolic flights offer a unique environment to study physiological changes under varying gravity.
Purpose of the Study:
- To analyze the activation area (AA) using the Decarto technique during parabolic flights.
- To investigate how gravitational changes affect cardiac electrical activity, specifically the AA.
Main Methods:
- Utilized the Decarto technique to analyze orthogonal ECGs from 23 subjects during parabolic flights.
- Compared AA values during horizontal flight, ascent, and initial microgravity.
- Subdivided subjects into three groups based on ventricular electrical activity.
Main Results:
- Activation area (AA) changes varied across subject groups and gravitational phases.
- In groups I and II, early QRS AA increased in microgravity and decreased in hypergravity.
- Late QRS AA increased in microgravity and decreased in hypergravity across all groups.
Conclusions:
- Observed differences in AA changes suggest varying responses to gravity based on ventricular dominance.
- The Brody effect may explain changes in groups I and II, while group III might involve blood volume shifts.
- Late QRS AA changes indicate a consistent response possibly due to depolarization front neutralization.