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Updated: Sep 29, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Early-onset neonatal sepsis caused by vertical transmission of Morganella morganii
Manuel Casanova-Román1, Antonio Sanchez-Porto, Manuel Casanova-Bellido
1Paediatrics Service, Hospital of La Línea, Cádiz, Spain. mcasanova@arrakis.es
Abstract:
The onset of Morganella morganii infection within the first 72 h after birth has only been reported on 1 occasion. The authors describe a second case in which M. morganii was cultured from both the neonate's blood and the mother's lochia. The infant was successfully treated with cefotaxime and gentamicin.
Insights
Early-onset Morganella morganii infection is rare, with only two reported cases. This study details a second instance of neonatal M. morganii sepsis, successfully treated with antibiotics.
Area of Science:
- Neonatal infections
- Bacterial pathogenesis
- Antimicrobial therapy
Background:
- Early-onset neonatal sepsis poses significant risks.
- Morganella morganii is an uncommon cause of neonatal infection.
- Limited data exists on M. morganii infections within 72 hours of birth.
Observation:
- A neonate presented with M. morganii infection shortly after birth.
- M. morganii was identified in both the infant's bloodstream and the mother's lochia.
- This represents the second reported case of such early-onset infection.
Findings:
- Successful treatment of neonatal M. morganii sepsis was achieved.
- Combination antibiotic therapy with cefotaxime and gentamicin proved effective.
- The case highlights potential vertical transmission from mother to neonate.
Implications:
- Clinicians should consider M. morganii in the differential diagnosis of early-onset neonatal sepsis.
- Prompt diagnosis and appropriate antibiotic selection are crucial for favorable outcomes.
- Further research is warranted to understand the epidemiology and risk factors for M. morganii neonatal infections.
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