[The prognosis of asthmatic children with status asthmatics in early childhood]
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Published on: November 4, 2010
Masaki Komatsu1, Kaori Ikematsu, Hiroshi Tachimoto
1Department of Pediatrics, National Sagamihara Hospital.
Insights
Status asthmaticus in children shows a good prognosis with appropriate treatment. Most children experienced reduced hospital admissions and symptom severity over time, with many becoming asthma-free.
Area of Science:
- Pediatric Pulmonology
- Allergy and Immunology
- Clinical Pediatrics
Context:
- Status asthmaticus in early childhood presents a significant clinical challenge.
- Long-term prognosis and treatment outcomes for these children require further elucidation.
- Retrospective analysis of patients treated at a single institution provides valuable insights.
Purpose:
- To evaluate the long-term prognosis of children experiencing status asthmaticus in early childhood.
- To assess the impact of treatment strategies on disease progression and outcomes.
- To identify factors influencing recovery and remission rates.
Summary:
- This study retrospectively analyzed 113 children treated for status asthmaticus between 1995-2000.
- Hospital admission frequency decreased significantly over five years post-episode.
- While initially severe, a substantial percentage showed reduced severity or became asthma-free within five years.
- Disodium cromoglycate (DSCG) inhalation and regular (RTC) therapy were primary treatments, with some requiring budesonide (BDI).
Impact:
- Appropriate and careful management of childhood status asthmaticus leads to a relatively good prognosis.
- Early childhood status asthmaticus does not necessarily imply a uniformly poor long-term outcome.
- Findings support continued research into optimal therapeutic interventions for pediatric asthma emergencies.
Abstract:
To clarify the prognosis of asthmatic children with status asthmatics in early childhood, we retrospectively investigated 113 patients (boys: 62, girls: 51) who had been treated as status asthmatics since 1995 through 2000 in National Sagamihara Hospital. In this study, the frequency of admission was decreased year by year, 62.8% (1st year), 29.2% (3rd year), and 5% (5th year). All patients were evaluated as severe or moderate patients during the 1st year from the episode of status asthmatics. Three years after the episode, 38% of patients were evaluated as severe or moderate patients. Five years later, only 20% of patients were evaluated as severe or moderate patients and 35% became free from treatment and asthma attack. Most of the patients were treated by DSCG inhalation and RTC therapy. Nine patients needed BDI therapy in addition to DSCG and RTC. With appropriate and careful treatment, the prognosis of the patients who had experienced status asthmatics in the early childhood was kept relatively well.
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