Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Material-specific analysis using coherent-scatter imaging.

Deidre L Batchelar1, Ian A Cunningham

  • 1Imaging Research Laboratories, The John P. Robarts Research Institute, London, Ontario, Canada.

Medical Physics
|August 31, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robust Fourier-based slanted-edge method to measure scatter ratio.

Medical physics·2025
Same author

Can processed images be used to determine the modulation transfer function and detective quantum efficiency?

Journal of medical imaging (Bellingham, Wash.)·2024
Same author

Reduced Total Airway Count and Airway Wall Tapering after Three-Years in Ex-Smokers.

COPD·2023
Same author

Theoretical comparison of energy-resolved and digital-subtraction angiography.

Medical physics·2022
Same author

Frequency-dependent signal and noise in spectroscopic x-ray imaging.

Medical physics·2020
Same author

Cascaded systems analysis of charge sharing in cadmium telluride photon-counting x-ray detectors.

Medical physics·2018
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Coherent-scatter computed tomography (CSCT) offers material-specific imaging by analyzing tissue scatter properties. This novel method accurately quantifies bone mineral density, demonstrating its potential for densitometry.

Area of Science:

  • Medical Imaging
  • Materials Science
  • Physics

Background:

  • Coherent-scatter computed tomography (CSCT) utilizes low-angle X-ray scatter (<10 degrees) for imaging.
  • Tissue scatter properties depend on molecular structure, enabling material-specific mapping.
  • Current goals focus on quantitative mapping of bone-mineral content.

Purpose of the Study:

  • To develop and validate a novel imaging method, CSCT, for quantitative material analysis.
  • To achieve accurate bone mineral density (BMD) measurements using CSCT.
  • To demonstrate the viability of CSCT for densitometry applications.

Main Methods:

  • Acquired scatter patterns using a diagnostic X-ray source and image intensifier under first-generation CT geometry.
  • Implemented corrections for exposure fluctuations, intensifier lag (convolution method), and self-attenuation (primary beam measurement).

Related Experiment Videos

  • Validated quantitative measurements using poly(methyl methacrylate) (PMMA) and hydroxyapatite-infused acrylic phantoms simulating bone.

    • Main Results:

    • Corrected CSCT images allowed for quantitative material density measurements (g/cm3).
    • Corrections for lag and self-attenuation were successfully implemented with negligible noise impact.
    • Experimental results showed excellent agreement between known and measured BMD in phantoms.

    Conclusions:

    • CSCT, with implemented corrections, provides accurate quantitative measurements of material composition.
    • The method demonstrated high fidelity in determining bone mineral density.
    • CSCT shows significant potential as a viable tool for densitometry.