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Depressive symptoms predict 12-month prognosis in elderly patients with acute myocardial infarction

Issei Shiotani1, Hiroshi Sato, Kunihiro Kinjo

  • 1Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan.

Journal of Cardiovascular Risk
|August 31, 2002
PubMed

Insights

Depression after acute myocardial infarction (AMI) increases cardiac event risk, particularly in elderly patients. Identifying and managing these depressive symptoms is crucial for better patient outcomes.

Area of Science:

  • Cardiology
  • Psychiatry
  • Geriatrics

Background:

  • Depressive symptoms are linked to increased cardiac event risk post-acute myocardial infarction (AMI).
  • This study investigates the impact of depression on the prognosis of elderly patients experiencing AMI.

Purpose of the Study:

  • To determine if depressive symptoms influence the 1-year prognosis of elderly patients with AMI.
  • To assess the association between depression and cardiac events following AMI.

Main Methods:

  • 1042 patients with AMI were assessed for depression using the Zung Self-Rating Depression Scale (SDS).
  • Patients scoring >= 40 were classified as having depressive symptoms.
  • Cardiac events were monitored over a 12-month follow-up period.

Main Results:

  • 42% of patients exhibited depressive symptoms; prevalence was not dependent on age or gender.
  • Patients with depressive symptoms had a 31.2% annual cardiac event rate versus 23.9% in others.
  • Depression significantly predicted 1-year cardiac events (OR 1.41), especially in elderly patients (>= 65 years).

Conclusions:

  • Post-AMI depression is a significant predictor of 1-year cardiac events in the Japanese population.
  • Depression augments cardiac event risk, particularly in elderly patients after AMI.
Abstract

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