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[Effect of Ganoderma polysaccharides on cAMP in murine peritoneal macrophages]
1Department of Pharmacy, Navy 401 Hospital, Shandong, Qingdao 266071, China.
Abstract
Objective:
Investigating the effect of GLB7 on cAMP in murine peritoneal macrophages to provide a scientific evidence for the immunomodulatory mechanism.
Method:
Cell culture and radio-immunological assay of cAMP were used.
Result:
GLB7 increased the production of cAMP in a concentration and time dependent manner in murine peritoneal macrophages.
Conclusion:
The immunopotentiating effect of GLB7 may be due to the activation of macrophages that leads to the increase of cAMP.