Related Experiment Video
Updated: Aug 7, 2026
The Establishment of a Lung Colonization Assay for Circulating Tumor Cell Visualization in Lung Tissues
Published on: June 16, 2018
Choroidal metastasis in disseminated lung cancer: frequency and risk factors
Klaus-Martin Kreusel1, Thomas Wiegel, Marit Stange
1Department of Ophthalmology, University Hospital Benjamin Franklin, Free University of Berlin, Germany. kmkreusel@aol.com
Purpose:
To determine frequency, risk factors, and benefit of a prospective screening for intraocular metastasis in patients with metastatic lung cancer.
Design:
Consecutive observational case series.
Methods:
An ophthalmologic screening was performed on 84 consecutive patients suffering from metastatic lung cancer. Medical history and disease stage were evaluated in regard to the risk for intraocular metastasis.
Results:
In six patients (7.1%) choroidal metastasis (CM) was detected. Choroidal metastasis was present only when at least two other organ system were affected by metastasis (P =.03). The choroid was the sixth common site of organ metastasis. Mean remaining life span in patients with CM was 1.9 (0.2-5.9) months.
Conclusions:
Choroidal metastasis is common in advanced metastatic lung cancer. However, due to the short survival of affected individuals, a systematic screening of at-risk patients for CM seems to be of limited benefit.
