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Genomics in pure and applied entomology
1Centre for Environmental Stress and Adaptation Research, Department of Genetics, The University of Melbourne, Parkville, Victoria 3010, Australia. dheckel@unimelb.edu.au
Annual Review of Entomology
|September 5, 2002
Summary
Genomics, the study of an organism's complete set of DNA, uses new technologies for genome sequencing and functional analysis. This advances understanding of complex traits and gene expression, crucial for fields like entomology.
Area of Science:
- Genomics and Molecular Biology
- Genetics
- Bioinformatics
Background:
- Genomics involves studying the genome, the complete set of genetic information in an organism's DNA.
- Recent technological advancements have revolutionized genomic research, enabling large-scale studies.
- The field integrates traditional biological inquiry with cutting-edge approaches.
Purpose of the Study:
- To highlight the advancements in genomics driven by technological developments.
- To explain the shift towards genome-wide functional studies.
- To emphasize the importance of genomics in applied fields like entomology.
Main Methods:
- Whole-genome sequencing to determine gene order and organization.
- Development of DNA fragment libraries for physical access.
- Genome-wide functional studies, including gene expression analysis and gene disruption.
Main Results:
- Enabling comprehensive analysis of the genetic basis of complex traits.
- Facilitating quantification of global gene expression patterns.
- Providing tools for systematic gene disruption projects.
Conclusions:
- Genomics has enabled functional studies on a genome-wide scale.
- Collaboration between public and private sectors is vital for applying genomic knowledge.
- Building upon existing genomic data, such as the Drosophila genome, can accelerate progress in other insect orders for applied entomology.