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Signalling through nuclear receptors.

Jamshed R Tata1

  • 1National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.

Nature Reviews. Molecular Cell Biology
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Summary
This summary is machine-generated.

Pancreatic secretions were identified as hormones a century ago. Advances in technology continue to deepen our understanding of hormone action from ductless glands.

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Area of Science:

  • Endocrinology
  • Biochemistry

Background:

  • Hormones, initially identified in pancreatic secretions a century ago, are now known to be produced by all ductless glands.
  • The study of endocrine secretions has evolved significantly over the past century.

Observation:

  • Pancreatic secretions were historically termed 'hormones'.
  • Ductless glands are now recognized as the primary source of hormones throughout the body.

Findings:

  • The historical classification of pancreatic secretions as hormones laid the groundwork for modern endocrinology.
  • Hormones are integral signaling molecules secreted by various ductless glands.

Implications:

  • Technological advancements are crucial for elucidating the complex mechanisms of hormone action.
  • Continued research promises further insights into the physiological roles and therapeutic potential of hormones.