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[Stable life prediction for a complex injection of Chinese materia medica by initial average rate stability test]
Abstract
Objective:
To predict the stable life for a complex injection of Chinese materia medica.
Method:
The prediction was carried out by initial average rate stability tests, and the contents of puerarin and danshensu (major active components of the injection) were assayed by HPLC.
Result:
The degradation of puerarin followed the first order action, while danshensu was hard to determine; the t0.9,25 degrees C was 3.49 years and 1.69 years respectively.
Conclusion:
The stable life of the injection has been determined as 1.5 years.