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Updated: Sep 29, 2026

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models
Published on: May 3, 2017
[Effect of qingkailing on glutamate and NMDA receptor of brain tissue]
1Department of Pediatrics, Xiangya Hospital, Hunan Medical University, Changsha 410008.
Abstract:
The effects of QingKaiLing on the content of glutamate(Glu) and gamma-aminobutyric acid(GABA), and the numbers and affinity of N-methyl-D-aspartate (NMDA) receptor in brain tissue were observed. QingKaiLing did not change the content of Glu and GABA and the ratio of Glu/GABA in brain tissue (P > 0.05). The numbers of NMDA receptor on membrane of neuron were significantly decreased in QingKaiLing group(P < 0.05). These results suggested that the brain protective mechanism of QingKaiLing be in relation to decreasing the numbers of NMDA receptor.
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