[A morphometric study on the microvessel in oral submucous fibrosis]

To investigate the pathologic change of the microvessel in oral submucous fibrosis(OSF), the pathologic buccal tissues of 27 patients with OSF were studied by using immunochemical method. Microvessel quantity(MVQ), quantity density(QD), microvessel area(MVA) and area density(AD) were determined by means of computer-aided image analysis system. The results showed the increase in MVQ and QD in the early stage and the decrease in MVQ, QD, MVA and AD in the middle stage and the late stage. The authors concluded that presence of microvessel hyperplasia occurred in the early stage of OSF.