Anthropometric finding in Nigerian children with sickle cell disease

Related Experiment Video

Updated: Sep 29, 2026

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

Folakemi A Oredugba1, Kofo O Savage

  • 1Department of Child Dental Health, College of Medicine, University of Lagos, Nigeria. tored@nova.net.ng

Pediatric Dentistry
|September 6, 2002
PubMed

Insights

Sickle cell disease (SCD) patients show higher rates of maxillary protrusion and Class II malocclusion. While overall height and weight were similar, SCD subjects weighed less at 18 years old.

Area of Science:

  • Medical Science
  • Genetics
  • Pediatrics

Background:

  • Sickle cell disease (SCD) is associated with anthropometric deficits like malocclusion and stunting.
  • Previous reports suggest variations in physical development among SCD patients.

Purpose of the Study:

  • To investigate the prevalence of anthropometric deficits in children with sickle cell disease in Lagos.
  • To compare facial profile and occlusion between SCD subjects and unaffected controls.

Main Methods:

  • A cross-sectional study involving 177 SCD subjects (ages 1-18) and 122 controls.
  • Measurements included facial profile, occlusion, height, weight, and head and mid-upper arm circumference.
  • Data collected from outpatient SCD units and well-baby/surgical emergency clinics.

Main Results:

  • SCD subjects exhibited a higher prevalence of prognathic maxillary profile (21% vs 4%) and Class II malocclusion (21% vs 2%).
  • No significant differences in overall mean height, weight, or head circumference between groups.
  • SCD subjects at 18 years weighed significantly less than controls, and controls had higher MUA circumference.

Conclusions:

  • Sickle cell disease is linked to increased maxillary protrusion and Class II malocclusion.
  • Height and weight differences were minimal, except for lower weight in 18-year-old SCD subjects.
  • Anthropometric variations in SCD patients warrant further investigation.
Abstract

More Related Videos

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts07:56

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Related Concept Videos

Nature and Nurture01:10

Nature and Nurture

Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience, such as differences...
Variation: Normal Distribution, Range, and Standard Deviation02:32

Variation: Normal Distribution, Range, and Standard Deviation

In the field of psychology, there are several ways to organize measurements of a trait, feature, or characteristic (i.e., variables). Qualitative data, such as ethnicity, can be tabulated into a frequency count to provide information about the proportion, as well as the variety of groups in a sample or population. On the other hand, researchers can perform a wider set of calculations on quantitative data. The mean, mode, and median, for instance, are central tendency measures to identify a...