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Persistent asthma: disease control, resource utilisation and direct costs.

E Van Ganse1, L Laforest, G Pietri

  • 1Pharmacoepidemiology Unit, and Poison Centre, Claude-Bernard University, Lyon, France. eric.vanganse@chu-lyon.fr

The European Respiratory Journal
|September 6, 2002
PubMed
Summary

Optimizing asthma management significantly reduces healthcare costs. Poorly controlled persistent asthma leads to higher medical resource utilization and expenses, highlighting the importance of adherence to prescribed therapies.

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Area of Science:

  • Pulmonary Medicine
  • Health Economics

Background:

  • Asthma management optimization is linked to fewer adverse outcomes, yet its impact on medical resource utilization (MRU) across different control and severity levels remains unclear.
  • Persistent asthma affects a significant population, necessitating an understanding of factors influencing healthcare costs.

Purpose of the Study:

  • To investigate the relationship between asthma control levels, disease severity, and medical resource utilization in adult patients with persistent asthma in France.
  • To quantify the economic impact of asthma control on healthcare costs.

Main Methods:

  • A retrospective study using a French family practice database (1998) identified 1,038 adult patients (17-50 years) with persistent asthma (GINA ≥ 2).
  • Patient surveys collected data on asthma control, hospital contacts, and demographics.

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  • Medical resource utilization costs over 12 months were analyzed in relation to patient characteristics, asthma control, and prior inhaled corticosteroid use.

    • Main Results:

    • Mean annual MRU costs were €549.8 for well-controlled, €746.3 for moderately controlled, and €1,451.3 for poorly controlled persistent asthma.
    • Costs significantly increased with age, comorbidities, recent asthma symptoms, and prior inhaled corticosteroid prescription.
    • Patients with poorly controlled asthma incurred substantially higher healthcare costs.

    Conclusions:

    • Significant variations in medical resource utilization exist based on asthma control and severity in persistent asthma patients.
    • Appropriate adherence to prescribed asthma control therapies can potentially reduce healthcare resource utilization and associated costs.