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Updated: Sep 14, 2026

Principles of Rodent Surgery for the New Surgeon
Published on: January 6, 2011
Management of Infection in the Surgical Patient
Ian D McGilvray1, Ori D Rotstein
1Research Fellow, Division of General Surgery, University of Toronto, Toronto, Canada.
Abstract:
While surgical infections are seemingly a heterogeneous group of disease entities, there are several common features that permit a general approach to their diagnosis and management. These properties include: the polymicrobial nature of the flora in most infections, the association of the infection with some underlying pathological process, and appropriate treatment often includes both broad-spectrum antimicrobial therapy and some surgical or radiological intervention to promote eradication of the infection. For the purpose of this review, intra-abdominal infection will be used as the prototypical surgical infection because it embodies many of the general features of most infections.
Insights
Surgical infections, often polymicrobial and linked to underlying pathology, require broad-spectrum antibiotics and surgical intervention for effective management. Intra-abdominal infections serve as a key model for understanding these complex conditions.
Area of Science:
- Infectious Diseases
- Surgical Pathology
- Microbiology
Background:
- Surgical infections present diverse clinical pictures but share common diagnostic and management principles.
- Key shared features include polymicrobial etiology, association with underlying pathological processes, and the need for combined antimicrobial and procedural interventions.
- Intra-abdominal infections are utilized as a representative model due to their embodiment of these general characteristics.
Purpose of the Study:
- To outline a generalizable approach to the diagnosis and management of surgical infections.
- To highlight common features across different types of surgical infections.
- To use intra-abdominal infections as a prototypical example to illustrate these principles.
Main Methods:
- Review of common features in surgical infections.
- Analysis of diagnostic and management strategies.
- Case study approach using intra-abdominal infections as a model.
Main Results:
- Surgical infections are frequently polymicrobial.
- An underlying pathological process is typically associated with surgical infections.
- Effective treatment combines broad-spectrum antimicrobial therapy with surgical or radiological intervention.
Conclusions:
- A unified approach to surgical infection diagnosis and management is feasible due to shared characteristics.
- Intra-abdominal infections exemplify the typical features and treatment paradigms for surgical infections.
- Combined medical and surgical strategies are crucial for eradicating most surgical infections.
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